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KMID : 0043320100330050647
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Archives of Pharmacal Research
2010 Volume.33 No. 5 p.647 ~ p.654
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Antimicrobial Activity of New 4,6-Disubstituted Pyrimidine, Pyrazoline, and Pyran Derivatives
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Adel A. H. Abdel-Rahman
Mahmoud M. M. Ramiz
Wael A. El-Sayed
Asmaa I. El-Tantawy
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Abstract
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A number of new 2,6-didisubstituted pyrimidine, pyrazoline, and pyran derivatives were synthesized starting from their chalcone derivative. The synthesized compounds displayed different degrees of antimicrobial activity against Bscillus subtilis (Gram-positive), Pseudomonas aeruginosa (Gram-negative), and Streptomyces species (Actinomycetes).
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KEYWORD
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Pyrimidines, Pyrazolines, Pyrans, Antimicrobial activity
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